Article originally published in Fierce Healthcare / July 28, 2026
LifeBridge Health’s Sinai Hospital of Baltimore is putting an artificial intelligence-powered diagnostic for sepsis into clinical use, bringing a research-backed tool to the patients’ bedside.
Chicago-based Prenosis, a biology-based technology company, developed Sepsis ImmunoScore®, an AI-powered tool that can spot the early signs of sepsis. The tool analyzes 22 parameters to identify patterns in a patient’s biological immune response, enabling clinicians to detect sepsis, or the progression to sepsis within 24 hours.
Sepsis ImmunoScore received the U.S. Food and Drug Administration’s first authorization for software to diagnose sepsis in 2024. Prenosis’ solution was approved through the FDA’s De Novo pathway. Sinai Hospital of Baltimore was among 10 research centers nationwide whose patient samples contributed to the 100,000-sample dataset that trained and validated the Prenosis algorithm. LifeBridge Health, which operates five hospitals and specialized care facilities in Maryland, has a long-standing relationship with the company as health system researchers contributed to the foundational study that enabled FDA authorization of the tool.