Science

Science, technology and the emergence of AI have converged to make precision medicine for acute care a reality. This is how we deliver healthcare tailored to biology.

Research & Development

NOSIS™

Partners

Evidence

The Sepsis ImmunoScore® Predicts Sepsis, Mortality, and Deterioration Better than Clinical Scores and Widely Available Biomarkers

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Platform

Prenosis is developing a pipeline of integrated diagnostics and therapeutics grounded in each patient's unique biological profile, using deep data science and AI to give clinicians tools that reflect the true complexity of critical disease.

Sepsis ImmunoScore®

Clinical Trials

Pipeline

BioAegis Therapeutics Announces Collaboration with Prenosis to Advance AI-Driven Precision Medicine in Inflammatory Disease

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Resources

Blogs, articles, videos, and podcasts exploring how precision medicine and AI are changing the way clinicians detect and treat critical conditions.

Newsroom

Resource Library

Events

Why We Call It an “AI-Biomarker”

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Newsroom

Read the latest Prenosis peer-reviewed articles and items from scholarly journals.

Newsroom

Sepsis ImmunoScore Outperforms Conventional Sepsis Tools

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About

As a biology-based technology company, we combine data science with AI to transform how critical conditions are diagnosed and treated.

Mission, Vision & Values

Careers

Leadership

Investors

Awards

Prenosis and Winners of the Chicago Innovation Awards Ring the Opening Nasdaq Bell

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AI-Powered Precision Therapeutics for Acute Illness

Our mission is to tailor healthcare to each patient’s biology by developing and delivering precision therapeutics, so each person receives the treatment they deserve.

Devastating Conditions. No Targeted Treatments.

Every patient reacts differently to acute illness like sepsis, pneumonia, and ARDS. Why? Because every patient is biologically different. Treatments that help one patient can harm another.

We spend 10 times more on acute conditions than we do on oncology. Yet there have been no novel therapeutics in this space in decades, leaving the largest unmet need in healthcare, and representing a massive market opportunity. 

Prenosis is the only company that is aligning AI, technology, and biology to develop precision therapeutics.

Spend Per Year Worldwide

Why Treatments Have Failed

Solving Patient Heterogeneity.

Patients with the same clinical diagnosis can have very different underlying biology and very different responses to treatment.

 

Conventional clinical trials and treatment protocols often fail to account for this heterogeneity, obscuring the patients who may benefit.

Using AI-powered deep biological profiling, Prenosis makes those differences visible and actionable.

The Platform Behind the Mission

AI-Powered.
Biology-Driven.
EHR-Integrated.

Our proprietary, EHR-integrated software connects one of the largest acute-illness biobanks in existence to a continuously growing multimodal dataset, using powerful AI models to identify which patients are most likely to respond to which treatment, and deliver that insight to clinicians in real time.

Our platform continuously maps the biology behind immune-driving disease – turning that insight into a growing pipeline of precision therapeutics – making it more precise with every patient treated.

End-to-End Infrastructure

Enabling a New Class of Precision Therapeutics

The solution? Prenosis is building the infrastructure through which precision therapeutics are discovered, developed, validated, and delivered

 

The data that makes targeted treatment possible

Prenosis has built one of the largest acute-illness biobanks in existence: more than 140,000 longitudinal biospecimens from more than 35,000 patients, growing through a network of leading clinical research sites. AI translates that biology into insight about which treatment will work for which patient.​

Discover →

 

From signal to precision therapeutics

AI-Biomarkers integrate multiple types of data to show which patients will respond to which treatments. We apply them to mature drug candidates, redefining patient populations and improving the odds of late-stage success.

Develop →

The clinical network that proves what works

We’ve reimagined clinical trial methodology for critical illness. Our biology-first clinical trial infrastructure simultaneously generates data, reveals new therapeutic-response populations, validates therapeutics, and identifies appropriate patients for targeted treatment in real-time.

Validate →

The software that uses AI to surface biological insights

Our Immunix® platform is the engine that identifies, clinically validates, and delivers precision therapeutics. Its first commercial application, Sepsis ImmunoScore®, is the first-ever FDA-authorized AI diagnostic for sepsis, and the first step in an expanding pipeline of precision therapeutics.

Deliver →

In The News

Stay Updated on the Latest Media and News Coverage

August 31, 2026

Prenosis and Winners of the Chicago Innovation Awards Ring the Opening Nasdaq Bell

August 27, 2026

Precision Medicine Transformed Oncology — It’s Time to Do the Same for Sepsis

July 28, 2026

LifeBridge Health deploys Prenosis’ FDA-authorized AI tool to speed sepsis detection